Correction of abnormal B-cell subset distribution by interleukin-6 receptor blockade in polymyalgia rheumatica.
Identifieur interne : 001860 ( Main/Exploration ); précédent : 001859; suivant : 001861Correction of abnormal B-cell subset distribution by interleukin-6 receptor blockade in polymyalgia rheumatica.
Auteurs : Guillermo Carvajal Alegria ; Valérie Devauchelle-Pensec ; Yves Renaudineau [France] ; Alain Saraux ; Jacques-Olivier Pers [France] ; Divi CornecSource :
- Rheumatology (Oxford, England) [ 1462-0332 ] ; 2017.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Anticorps monoclonaux humanisés (administration et posologie), Cytokines (sang), Cytométrie en flux, Femelle, France, Humains, Indice de gravité médicale, Interleukine-6 (antagonistes et inhibiteurs), Interleukine-6 (sang), Mâle, Rhumatisme inflammatoire des ceintures (sang), Rhumatisme inflammatoire des ceintures (traitement médicamenteux), Sous-populations de lymphocytes B (), Sous-populations de lymphocytes T, Sujet âgé, Test ELISA, Études cas-témoins, Études prospectives.
- MESH :
- administration et posologie : Anticorps monoclonaux humanisés.
- antagonistes et inhibiteurs : Interleukine-6.
- sang : Cytokines, Interleukine-6, Rhumatisme inflammatoire des ceintures.
- traitement médicamenteux : Rhumatisme inflammatoire des ceintures.
- Adulte d'âge moyen, Cytométrie en flux, Femelle, France, Humains, Indice de gravité médicale, Mâle, Sous-populations de lymphocytes B, Sous-populations de lymphocytes T, Sujet âgé, Test ELISA, Études cas-témoins, Études prospectives.
English descriptors
- KwdEn :
- Aged, Antibodies, Monoclonal, Humanized (administration & dosage), B-Lymphocyte Subsets (drug effects), Case-Control Studies, Cytokines (blood), Enzyme-Linked Immunosorbent Assay, Female, Flow Cytometry, France, Humans, Interleukin-6 (antagonists & inhibitors), Interleukin-6 (blood), Male, Middle Aged, Polymyalgia Rheumatica (blood), Polymyalgia Rheumatica (drug therapy), Prospective Studies, Severity of Illness Index, T-Lymphocyte Subsets.
- MESH :
- chemical , administration & dosage : Antibodies, Monoclonal, Humanized.
- chemical , antagonists & inhibitors : Interleukin-6.
- chemical , blood : Cytokines, Interleukin-6.
- blood : Polymyalgia Rheumatica.
- drug effects : B-Lymphocyte Subsets.
- drug therapy : Polymyalgia Rheumatica.
- Aged, Case-Control Studies, Enzyme-Linked Immunosorbent Assay, Female, Flow Cytometry, France, Humans, Male, Middle Aged, Prospective Studies, Severity of Illness Index, T-Lymphocyte Subsets.
Abstract
The aim was to study lymphocyte subsets and circulating cytokines at diagnosis of PMR and after tocilizumab monotherapy.
DOI: 10.1093/rheumatology/kex169
PubMed: 28431111
Affiliations:
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Le document en format XML
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Index</term><term>T-Lymphocyte Subsets</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Cytométrie en flux</term><term>Femelle</term><term>France</term><term>Humains</term><term>Indice de gravité médicale</term><term>Mâle</term><term>Sous-populations de lymphocytes B</term><term>Sous-populations de lymphocytes T</term><term>Sujet âgé</term><term>Test ELISA</term><term>Études cas-témoins</term><term>Études prospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The aim was to study lymphocyte subsets and circulating cytokines at diagnosis of PMR and after tocilizumab monotherapy.</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Région Bretagne</li></region><settlement><li>Brest</li></settlement><orgName><li>Université de Bretagne Occidentale</li><li>Université européenne de Bretagne</li></orgName></list><tree><noCountry><name sortKey="Carvajal Alegria, 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